Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 5/20 | 0.43 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616377 | 0.81 | BCAT2 (0.47) | BCAT2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29002505 | 0.79 | KDM4E (0.53) | BCAT2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4504523 | 0.79 | JAK2 (0.49) | BCAT2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1533665 | 0.76 | PARP1 (0.54) | BCAT2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30017135 | 0.75 | KDM4E (0.40) | BCAT2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28639243 | 0.75 | KDM4E (0.40) | BCAT2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30733977 | 0.74 | DGAT1 (0.42) | MEN1KMT2AKDM4EALDH1A1PARP1 | |
| SCHEMBL2762235 | 0.74 | DGAT1 (0.42) | MEN1KMT2AKDM4EALDH1A1PARP1 | |
| SCHEMBL30641935 | 0.74 | DGAT1 (0.42) | MEN1KMT2AKDM4EALDH1A1PARP1 | |
| Benzoic Acid SCHEMBL28961466 | 0.73 | TSHR (0.45) | BCAT2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |
| CN-1176908-C | Process for producing pyridine derivate | - | 2004-11-24 | — | — | CN | disclosed |
| CN-1297887-A | Process for producing pyridine derivate | HOFFMANN LA ROCHE (CH) | 2001-06-06 | — | — | CN | disclosed |