Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 15/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 15/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783896 | 0.74 | CYP1A2 (0.33) | — | |
| SCHEMBL4781804 | 0.72 | GPR119 (0.37) | — | |
| SCHEMBL14292741 | 0.72 | MIF (0.38) | — | |
| SCHEMBL14293541 | 0.70 | — | — | |
| SCHEMBL4781141 | 0.70 | ESRRA (0.38) | — | |
| SCHEMBL13436193 | 0.62 | FLT3 (0.34) | — | |
| SCHEMBL4781912 | 0.62 | HTT (0.36) | — | |
| SCHEMBL14688544 | 0.61 | — | — | |
| SCHEMBL15869706 | 0.61 | BRAF (0.51) | — | |
| SCHEMBL14909053 | 0.61 | NOTUM (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |