Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 9/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293533 | 0.82 | KMT2A (0.34) | ESRRA | |
| SCHEMBL4781804 | 0.76 | GPR119 (0.37) | ESRRA | |
| SCHEMBL14292741 | 0.76 | MIF (0.38) | ESRRA | |
| SCHEMBL4783896 | 0.71 | CYP1A2 (0.33) | LRRK2 | |
| SCHEMBL4782117 | 0.70 | TEK (0.41) | IRAK4 | |
| SCHEMBL4782676 | 0.70 | RXRA (0.34) | — | |
| SCHEMBL14293540 | 0.69 | RXRA (0.34) | ESRRALRRK2 | |
| SCHEMBL14293541 | 0.68 | — | — | |
| SCHEMBL14023204 | 0.67 | FFAR1 (0.37) | GLA | |
| SCHEMBL14293383 | 0.65 | RXRA (0.35) | ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |