Sugi Predict

Sugi Predict / Compounds / SCHEMBL4782791

SCHEMBL4782791

SCHEMBL4782791

CC(=O)Oc1ccc2c(c1)CC(NS(=O)(=O)c1ccccc1C(C)C)C2

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ NR1H2 P55055 14/20 0.41
▸ GRIA2 P42262 2/20 0.40
▸ DRD2 P14416 1/20 0.39
▸ HTR6 P50406 1/20 0.39
▸ NR1H3 Q13133 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4784133 0.89 NR1H2 (0.40) MEN1KMT2ANR1H2GRIA2DRD2
SCHEMBL4783093 0.84 PSEN1 (0.43) NR1H2DRD2HTR6
SCHEMBL4782325 0.83 NR1H2 (0.48) MEN1KMT2ANR1H2NR1H3
SCHEMBL4784495 0.83 CA1 (0.44) MEN1KMT2ANR1H2GRIA2DRD2
SCHEMBL4782205 0.82 CA1 (0.50) MEN1KMT2ADRD2HTR6
SCHEMBL4781448 0.82 NR1H2 (0.57) MEN1KMT2ANR1H2GRIA2
SCHEMBL4797405 0.81 MAPT (0.43) MEN1KMT2ANR1H2GRIA2DRD2
SCHEMBL4781653 0.78 KDM4E (0.43) MEN1KMT2ANR1H2NR1H3
SCHEMBL4781658 0.78 KDM4E (0.43) MEN1KMT2ANR1H2NR1H3
SCHEMBL4781505 0.78 TBXA2R (0.42) MEN1KMT2ANR1H2GRIA2DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008061006-A1 SUBSTITUTED INDAN-2-YL, TETRAHYDRONAPHTHALEN-2-YL, OR DIHYDR0-2H-CHR0MEN-3-YL ARYLSULFONAMIDES AND METHODS OF THEIR USE WYETH (US) 2008-05-22 — — WO claimed
WO-2008061006-A1 SUBSTITUTED INDAN-2-YL, TETRAHYDRONAPHTHALEN-2-YL, OR DIHYDR0-2H-CHR0MEN-3-YL ARYLSULFONAMIDES AND METHODS OF THEIR USE WYETH (US) 2008-05-22 — — WO disclosed