Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 5/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 8/20 | 0.36 |
| ▸ | RAF1 | P04049 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293386 | 0.89 | TEK (0.43) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4782886 | 0.88 | NR1I2 (0.38) | NR1I2ALDH1A1SMN1; SMN2LMNAGPR119 | |
| SCHEMBL4779210 | 0.87 | TEK (0.41) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4782117 | 0.86 | TEK (0.41) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4780202 | 0.86 | TEK (0.42) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4783784 | 0.85 | TEK (0.40) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4780039 | 0.85 | TEK (0.40) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4782878 | 0.84 | TEK (0.39) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4846574 | 0.84 | TEK (0.39) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4782881 | 0.84 | TEK (0.39) | TEKNR1I2BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |