Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782895 | 0.88 | TEK (0.41) | NR1I2GPR119CA1CA2CA9 | |
| SCHEMBL4779207 | 0.85 | NR1I2 (0.38) | NR1I2GPR119IRAK4 | |
| SCHEMBL4780027 | 0.83 | NR1I2 (0.36) | NR1I2GPR119IRAK4 | |
| SCHEMBL4783774 | 0.83 | NR1I2 (0.36) | NR1I2GPR119IRAK4 | |
| SCHEMBL4780817 | 0.82 | NR1I2 (0.36) | NR1I2GPR119IRAK4 | |
| SCHEMBL4781607 | 0.81 | ACKR3 (0.41) | NR1I2GPR119SMN1; SMN2TSHRIRAK4 | |
| SCHEMBL4782188 | 0.81 | MEN1 (0.42) | NR1I2ALDH1A1MEN1KMT2A | |
| SCHEMBL4780707 | 0.80 | NR1I2 (0.36) | NR1I2GPR119IRAK4 | |
| SCHEMBL4783140 | 0.80 | MAPK14 (0.36) | NR1I2 | |
| SCHEMBL4782621 | 0.80 | GLS (0.43) | NR1I2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |