Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855287 | 0.93 | PIK3CA (0.44) | PIK3CAESR2ESR1IDH1PFKFB3 | |
| SCHEMBL4784449 | 0.86 | PIK3CA (0.49) | PIK3CAPIK3CBPIK3CG | |
| SCHEMBL4784144 | 0.84 | IDH1 (0.42) | PIK3CAESR2ESR1IDH1PFKFB3 | |
| SCHEMBL4784052 | 0.82 | PIK3CA (0.38) | PIK3CAESR2ESR1IDH1PFKFB3 | |
| SCHEMBL4785148 | 0.82 | ESR1 (0.42) | PIK3CAESR2ESR1PFKFB3PRMT5 | |
| SCHEMBL4782612 | 0.81 | IDH1 (0.41) | PIK3CAESR2ESR1IDH1PFKFB3 | |
| SCHEMBL4781508 | 0.81 | PIK3CA (0.42) | PIK3CAESR2ESR1 | |
| SCHEMBL4784160 | 0.80 | PIK3CA (0.42) | PIK3CAESR2ESR1PFKFB3 | |
| SCHEMBL4785552 | 0.80 | PIK3CA (0.42) | PIK3CAESR2ESR1PFKFB3PIK3CB | |
| SCHEMBL4784501 | 0.80 | AOC3 (0.38) | PIK3CAESR2ESR1IDH1PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |