Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.49 |
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855287 | 0.88 | PIK3CA (0.44) | PIK3CA | |
| SCHEMBL4782980 | 0.86 | PIK3CA (0.44) | PIK3CAPIK3CGPIK3CB | |
| SCHEMBL4785203 | 0.84 | KDR (0.42) | PIK3CAMTORPIK3CGPIK3CBPIK3CD | |
| SCHEMBL4782724 | 0.83 | PIK3CA (0.57) | PIK3CAMTORPIK3CGPIK3CBPIK3CD | |
| SCHEMBL4784452 | 0.83 | PIK3CA (0.50) | PIK3CAMTORMEN1KMT2ALMNA | |
| SCHEMBL4784144 | 0.80 | IDH1 (0.42) | PIK3CAMTORMAPTALDH1A1MAPK1 | |
| SCHEMBL4784015 | 0.78 | HTR2A (0.44) | PIK3CAMTORMEN1KMT2ALMNA | |
| SCHEMBL4783015 | 0.78 | PIK3CA (0.48) | PIK3CAMTORPIK3CG | |
| SCHEMBL4784052 | 0.78 | PIK3CA (0.38) | PIK3CAMTORLMNACYP1A2CYP3A4 | |
| SCHEMBL4785148 | 0.78 | ESR1 (0.42) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |