Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | CNR2 | P34972 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472171 | 0.91 | PRKCZ (0.51) | CNR1CNR2MAOAMAOBPRKCZ | |
| SCHEMBL2991907 | 0.88 | CNR1 (0.64) | CNR1CNR2MAOAMAOBPRKCZ | |
| Hydrochloric Acid SCHEMBL2996363 | 0.86 | CNR1 (0.62) | CNR1CNR2MAOAMAOBPRKCZ | |
| SCHEMBL4783592 | 0.86 | MEN1 (0.54) | CNR1CNR2MAOAMAOBPRKCZ | |
| SCHEMBL4783428 | 0.84 | PRKCZ (0.53) | CNR1MAOAMAOBPRKCZMEN1 | |
| SCHEMBL3690744 | 0.83 | CNR1 (0.56) | CNR1CNR2MAOAMAOBPRKCZ | |
| SCHEMBL14396605 | 0.82 | CNR1 (0.58) | CNR1CNR2MAOAMAOBPRKCZ | |
| SCHEMBL4783707 | 0.81 | CNR1 (0.57) | CNR1CNR2MAOAMAOBPDE5A | |
| SCHEMBL14396247 | 0.81 | CNR1 (0.57) | CNR1CNR2MAOB | |
| SCHEMBL5599312 | 0.79 | PDE5A (0.48) | CNR1CNR2MAOAMAOBPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008062424-A2 | SUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | claimed |