Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695872 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL4488551 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL2048994 | 0.71 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL4731236 | 0.68 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL10588135 | 0.67 | ADRA2A (0.41) | ALDH1A1HPGDKDM4EDRD2LMNA | |
| SCHEMBL8890449 | 0.65 | KMT2A (0.53) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13113527 | 0.65 | MEN1 (0.57) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL1488973 | 0.65 | HPGD (0.42) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL11430784 | 0.65 | NOTUM (0.40) | ALDH1A1HPGDKDM4EDRD2 | |
| SCHEMBL4495800 | 0.64 | TSHR (0.52) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |