Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 4/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.38 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782714 | 0.99 | MAP2K4 (0.41) | MAP2K4MAPK1MAPK6KITCSNK2A1 | |
| Lithium Ion SCHEMBL4783272 | 0.86 | FGFR1 (0.38) | MAPK1KITCSNK2A1FGFR1FGFR2 | |
| SCHEMBL4785231 | 0.77 | POLB (0.50) | MAPK1MAPK8MAPK10MAPK14ITK | |
| SCHEMBL4784771 | 0.75 | LMNA (0.52) | MAPK1MAPK8MAPK10MAPK14 | |
| SCHEMBL4785918 | 0.75 | LSS (0.54) | MAPK1MAPK10MAPK14 | |
| SCHEMBL4782765 | 0.73 | ALDH1A1 (0.51) | MAPK1KITMAPK8MAPK10MAPK14 | |
| SCHEMBL31746650 | 0.71 | DYRK1A (0.52) | MAP2K4MAPK1MAPK6CSNK2A1MAPKAPK5 | |
| SCHEMBL1144879 | 0.71 | DYRK1A (0.52) | MAP2K4MAPK1MAPK6CSNK2A1MAPKAPK5 | |
| SCHEMBL3603415 | 0.71 | KMT2A (0.50) | MAP2K4MAPK1MAPK6MAPKAPK5MAPKAPK3 | |
| SCHEMBL922195 | 0.70 | PDPK1 (0.53) | MAP2K4MAPK1MAPK6CSNK2A1MAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153810-A1 | INDAZOLE DERIVATIVES USEFUL AS MELANIN CONCENTRATING RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-06-26 | — | — | US | disclosed |
| WO-2008061109-A2 | INDAZOLE DERIVATIVES USEFUL AS MELANIN CONCENTRATING RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153810-A1 | INDAZOLE DERIVATIVES USEFUL AS MELANIN CONCENTRATING RECEPTOR LIGANDS | MCHR1, MCHR2, MC1R | MAP2K4 4145/4885MAPK1 3438/4885MAPK6 3995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.