Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 18/20 | 0.46 |
| ▸ | WNT3 | P56703 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783395 | 1.00 | SFRP1 (0.46) | SFRP1WNT3HTR6HTR1AHTR7 | |
| SCHEMBL4785274 | 0.90 | SFRP1 (0.45) | SFRP1WNT3 | |
| SCHEMBL4785281 | 0.90 | SFRP1 (0.45) | SFRP1WNT3 | |
| SCHEMBL4783287 | 0.90 | HTR6 (0.47) | SFRP1WNT3HTR6HTR1AHTR7 | |
| SCHEMBL4783281 | 0.90 | HTR6 (0.47) | SFRP1WNT3HTR6HTR1AHTR7 | |
| SCHEMBL4780921 | 0.90 | SFRP1 (0.48) | SFRP1WNT3HTR6HTR1AHTR7 | |
| SCHEMBL4836991 | 0.89 | SFRP1 (0.45) | SFRP1WNT3HTR6HTR1AHTR7 | |
| SCHEMBL4781306 | 0.88 | SFRP1 (0.46) | SFRP1WNT3HTR6HTR1AHTR7 | |
| SCHEMBL4782529 | 0.88 | SFRP1 (0.56) | SFRP1WNT3HTR6 | |
| SCHEMBL4784256 | 0.88 | SFRP1 (0.46) | SFRP1WNT3HTR6HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |