Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PIK3R5 | Q8WYR1 | 2/20 | 0.40 |
| ▸ | PIK3R3 | Q92569 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709823 | 0.83 | NR1H4 (0.55) | NR1H4MAPTTP53POLB | |
| SCHEMBL9832871 | 0.79 | PTGS1 (0.49) | CYP1A2HIF1ACCNA2CDK2CCNA1 | |
| SCHEMBL4731309 | 0.78 | CNR2 (0.45) | NR1H4LMNACNR1 | |
| SCHEMBL4729577 | 0.78 | CNR1 (0.45) | LMNACNR1 | |
| SCHEMBL2492413 | 0.76 | CNR2 (0.52) | CNR1 | |
| SCHEMBL2186114 | 0.76 | CNR2 (0.42) | CCNA2CDK2CCNA1PIK3CDPIK3R2 | |
| SCHEMBL17385520 | 0.76 | CYP1A2 (0.35) | CYP1A2HIF1ACCNA2CDK2CCNA1 | |
| SCHEMBL9832064 | 0.75 | CCNA2 (0.35) | CYP1A2HIF1ACCNA2CDK2CCNA1 | |
| SCHEMBL11866077 | 0.75 | CYP1A2 (0.59) | CYP1A2HIF1ACCNA2CDK2CCNA1 | |
| SCHEMBL9833649 | 0.74 | PTGS1 (0.46) | CYP1A2HIF1ACCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |