SCHEMBL478386

SCHEMBL478386

CC(COCC(O)CO)OCC(O)CO

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
USP2 O75604 1/20 0.44
KDM4E B2RXH2 3/20 0.35
LMNA P02545 3/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 2/20 0.32
AGTR1 P30556 1/20 0.32
DUSP3 P51452 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21347319 0.98 TDP1 (0.48) TDP1USP2KDM4ELMNAALDH1A1
SCHEMBL20470494 0.92 TDP1 (0.44) TDP1USP2KDM4ELMNADUSP3
SCHEMBL550003 0.91 TDP1 (0.62) TDP1USP2KDM4ELMNAALDH1A1
SCHEMBL3902419 0.90 TDP1 (0.60) TDP1USP2KDM4ELMNAALDH1A1
SCHEMBL3899148 0.90 TDP1 (0.60) TDP1USP2KDM4ELMNAALDH1A1
SCHEMBL3902429 0.84 TDP1 (0.38) TDP1USP2KDM4ELMNAALDH1A1
SCHEMBL3899149 0.84 TDP1 (0.38) TDP1USP2KDM4ELMNAALDH1A1
SCHEMBL1838995 0.84 USP2 (0.45) TDP1USP2KDM4ELMNAALDH1A1
SCHEMBL4440314 0.83 LMNA (0.40) TDP1USP2KDM4ELMNAALDH1A1
Isobutane SCHEMBL27997158 0.83 USP2 (0.52) TDP1USP2KDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050220970-A1 Process for preparing a chewable pet food GAINES PET TREATS LIMITED (IE) 2005-10-06 US claimed
WO-2020158908-A1 TOPICAL COMPOSITION ロート製薬株式会社 2020-08-06 WO disclosed
EP-2412761-B1 INK COMPOSITION AND METHOD FOR PRODUCING DYED POLYAMIDE-BASED FIBER NIPPON KAYAKU KK (JP) 2016-08-31 EP disclosed
CN-103733003-B Cooling air conditioner compressor and refrigerating air conditioning device HITACHI APPLIANCES, INC. (JP) 2015-10-21 CN disclosed
CN-103733003-A Compressor for refrigeration and air conditioning, and refrigeration and air conditioning device HITACHI APPLIANCES INC 2014-04-16 CN disclosed
CN-101662896-B Method for manufacturing printed wiring board MEC CO LTD 2013-04-10 CN disclosed
EP-2412761-A1 INK COMPOSITION AND METHOD FOR PRODUCING DYED POLYAMIDE-BASED FIBER Nippon Kayaku Kabushiki Kaisha (JP) 2012-02-01 EP disclosed
US-7824534-B2 Copper electrolytic solution containing as additive compound having specific skeleton, and electrolytic copper foil manufactured therewith NIPPON MINING & METALS CO., LTD. (JP) 2010-11-02 US disclosed
US-20100224496-A1 Copper electrolytic solution containing as additive compound having specific skeleton, and electrolytic copper foil manufactured therewith NIPPON MINING & METALS CO., LTD. 2010-09-09 US disclosed
CN-101662896-A Method for manufacturing printed wiring board MEC CO LTD 2010-03-03 CN disclosed
US-20070170069-A1 Copper electrolytic solution containing as additive compound having specific skeleton, and electrolytic copper foil manufactured therewith JX NIPPON MINING & METALS CORPORATION (JP) 2007-07-26 US disclosed
US-6096692-A CYLIC KETALS AND ACDTALS HAVING HEAT AND OXIDATION RESISTANCE, ARE FREE FROM CARBOXYLIC ACIDS FORMING DUE TO HYDROLYSIS, LOW IN HYGROSCOPICITY, INEXPENSIVE, GOOD INSULATION AND COMPATIBLE WITH HYDROFLUOROCARBONS; WORKING FLUID REFRIGERANTS KAO CORPORATION (JP) 2000-08-01 US disclosed
CN-1161693-A Synthetic lubricating oil KAO CORP (JP) 1997-10-08 CN disclosed
EP-0779289-A1 SYNTHETIC LUBRICATING OIL Kao Corporation (JP) 1997-06-18 EP disclosed