SCHEMBL550003

SCHEMBL550003

CC(O)COC(C)COCC(O)CO

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.62
USP2 O75604 1/20 0.41
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 3/20 0.33
MAPK1 P28482 1/20 0.32
LMNA P02545 3/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 2/20 0.31
AGTR1 P30556 1/20 0.31
DUSP3 P51452 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3902419 0.98 TDP1 (0.60) TDP1USP2HSD17B10KDM4EMAPK1
SCHEMBL3899148 0.98 TDP1 (0.60) TDP1USP2HSD17B10KDM4EMAPK1
SCHEMBL478386 0.91 TDP1 (0.50) TDP1USP2HSD17B10KDM4EMAPK1
SCHEMBL21347319 0.89 TDP1 (0.48) TDP1USP2HSD17B10KDM4EMAPK1
SCHEMBL43392 0.87 TDP1 (0.71) TDP1HSD17B10KDM4EMAPK1LMNA
SCHEMBL18251589 0.86 TDP1 (0.56) TDP1USP2HSD17B10KDM4E
Water SCHEMBL15105007 0.84 TDP1 (0.68) TDP1HSD17B10KDM4EMAPK1LMNA
SCHEMBL204443 0.84 HSD17B10 (0.54) TDP1USP2HSD17B10KDM4EMAPK1
SCHEMBL250892 0.84 TDP1 (0.68) TDP1HSD17B10KDM4EMAPK1LMNA
SCHEMBL17504736 0.84 TDP1 (0.68) TDP1HSD17B10KDM4EMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111494291-A Blue light resisting and aging delaying skin care cosmetic and preparation method thereof 珠海越美科技有限公司 2020-08-07 CN claimed
CN-111095609-A Laser ablation for manufacturing battery cells 戴森技术有限公司 2020-05-01 CN claimed
EP-3292191-B1 ALKALINE DISHWASH COMPOSITION UNILEVER NV (NL) 2019-06-05 EP claimed
EP-3292191-A1 ALKALINE DISHWASH COMPOSITION Unilever N.V. (NL) 2018-03-14 EP claimed
WO-2016177563-A1 ALKALINE DISHWASH COMPOSITION UNILEVER N.V. (NL) 2016-11-10 WO claimed
US-20240018085-A1 SITE-SPECIFIC ISOTOPIC LABELING OF 1,4-DIENE SYSTEMS BIOJIVA LLC 2024-01-18 US disclosed
US-20230404960-A1 DISORDERS IMPLICATING PUFA OXIDATION BIOJIVA LLC (US) 2023-12-21 US disclosed
US-20220378734-A1 NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS RTMFP ENTERPRISES INC. 2022-12-01 US disclosed
US-20220133668-A1 ISOTOPICALLY MODIFIED COMPONENTS AND THERAPEUTIC USES THEREOF BIOJIVA LLC 2022-05-05 US disclosed
EP-3950649-A1 SITE-SPECIFIC ISOTOPIC LABELING OF 1, 4-DIENE SYSTEMS Retrotope, Inc. (US) 2022-02-09 EP disclosed
US-11241409-B2 Neurodegenerative disorders and muscle diseases implicating PUFAs RETROTOPE, INC. (US) 2022-02-08 US disclosed
EP-3943081-A1 OPTIC NEUROPATHY TREATMENT AND REDUCTION OF STEROID- INDUCED OXIDATIVE STRESS WITH STABILIZED POLYUNSATURATED SUBSTANCES Retrotope, Inc. (US) 2022-01-26 EP disclosed
US-20040096484-A1 Antioxidant-containing wipes and absorbent products for improving skin health KIMBERLY-CLARK WORLDWIDE, INC. 2004-05-20 US disclosed
US-20040024233-A1 Fatty acid esters composition of a polyglycerine, a process for the preparation thereof, a process for the preparation of a highly-purified fatty acid esters composition of a polyglycerine, a highly-purified fatty acid esters composition of a polyglycerine, an additive for food-stuffs, a resin composition, and a composition for cosmetics or detergents ENDO TOSHIO (JP) 2004-02-05 US disclosed
US-6403541-B1 NONIONIC SURFACTANT, POLYOXYALKYLENE ETHERS, POLYGLYCEROLS NEW JAPAN CHEMICAL CO., LTD. (JP) 2002-06-11 US disclosed
EP-1205535-A1 CLOGGING INHIBITOR FOR OIL FILTERS, METHOD FOR INHIBITING THE CLOGGING OF OIL FILTERS AND ENGINE OIL COMPOSITIONS CONTAINING THE INHIBITOR NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-05-15 EP disclosed
CN-1210549-A Preparation of double metal cyanide-catalyzed polyols by continuous addition of starter ARCO CHEM TECH (US) 1999-03-10 CN disclosed
CN-1014955-B Cosmetic preparation KAO CORP (JP) 1991-12-04 CN disclosed
CN-88100344-A Cosmetics 1988-08-10 CN disclosed
US-4014825-A POLYSILOXANES, POLYURETHANE FOAMS UNION CARBIDE CORPORATION (US) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018085-A1 SITE-SPECIFIC ISOTOPIC LABELING OF 1,4-DIENE SYSTEMS FADS1, FASN, FADS2 TDP1 2860/4885USP2 4218/4885HSD17B10 214/4885
US-20220378734-A1 NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS CPT1B, PSEN2, NLN TDP1 634/4885USP2 2305/4885HSD17B10 939/4885
US-11241409-B2 Neurodegenerative disorders and muscle diseases implicating PUFAs CPT1B, PSEN2, NLN TDP1 634/4885USP2 2305/4885HSD17B10 939/4885
US-20230404960-A1 DISORDERS IMPLICATING PUFA OXIDATION GPX4, CPT1A, FABP1 TDP1 3724/4885USP2 2680/4885HSD17B10 120/4885
US-20040024233-A1 Fatty acid esters composition of a polyglycerine, a process for the preparation thereof, a process for the preparation of a highly-purified fatty acid esters composition of a polyglycerine, a highly-purified fatty acid esters composition of a polyglycerine, an additive for food-stuffs, a resin composition, and a composition for cosmetics or detergents FASN, DGAT2, SCD5 TDP1 2812/4885USP2 2194/4885HSD17B10 103/4885
US-20220133668-A1 ISOTOPICALLY MODIFIED COMPONENTS AND THERAPEUTIC USES THEREOF ACADM, CPT1A, ALDH2 TDP1 3890/4885USP2 2109/4885HSD17B10 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.