Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.54 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.54 |
| ▸ | FASN | P49327 | 14/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736925 | 0.81 | FASN (0.58) | FASN | |
| SCHEMBL4736089 | 0.79 | FASN (0.57) | FASN | |
| SCHEMBL4734912 | 0.79 | FASN (0.59) | FASN | |
| SCHEMBL4735336 | 0.79 | FASN (0.65) | FASN | |
| SCHEMBL4732714 | 0.78 | PRSS12 (0.56) | UBE2MDCUN1D1FASNCCR1TP53 | |
| SCHEMBL4785488 | 0.78 | FASN (0.60) | FASN | |
| SCHEMBL4734570 | 0.77 | FASN (0.55) | FASN | |
| SCHEMBL4171986 | 0.76 | FASN (0.76) | FASN | |
| SCHEMBL4733073 | 0.76 | FASN (0.63) | FASN | |
| SCHEMBL4738019 | 0.76 | FASN (0.53) | FASNCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |