Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 16/20 | 0.48 |
| ▸ | MTTP | P55157 | 15/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783986 | 1.00 | APOB (0.48) | APOBMTTPNR1H2 | |
| SCHEMBL4784701 | 0.94 | APOB (0.47) | APOBMTTPNR1H2 | |
| SCHEMBL4784710 | 0.94 | APOB (0.47) | APOBMTTPNR1H2 | |
| SCHEMBL4783336 | 0.92 | APOB (0.46) | APOBMTTPNR1H2 | |
| SCHEMBL4783344 | 0.92 | APOB (0.46) | APOBMTTPNR1H2 | |
| SCHEMBL4782255 | 0.91 | NR1H2 (0.46) | APOBMTTPNR1H2 | |
| SCHEMBL4782252 | 0.91 | NR1H2 (0.46) | APOBMTTPNR1H2 | |
| SCHEMBL4780014 | 0.90 | NR1H2 (0.45) | APOBMTTPNR1H2 | |
| SCHEMBL4780011 | 0.90 | NR1H2 (0.45) | APOBMTTPNR1H2 | |
| SCHEMBL4780662 | 0.89 | NR1H2 (0.43) | APOBMTTPNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061006-A1 | SUBSTITUTED INDAN-2-YL, TETRAHYDRONAPHTHALEN-2-YL, OR DIHYDR0-2H-CHR0MEN-3-YL ARYLSULFONAMIDES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |