Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739542 | 0.86 | PARP1 (0.45) | NOTUMSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL21405164 | 0.85 | TMEM97 (0.49) | SMN1; SMN2NPC1RAB9AL3MBTL1CYP2C19 | |
| SCHEMBL21405534 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AL3MBTL1CYP2C19 | |
| SCHEMBL9051840 | 0.81 | NPC1 (0.41) | SMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL16372322 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AL3MBTL1CYP2C19 | |
| SCHEMBL9052963 | 0.78 | TACR3 (0.43) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15352654 | 0.78 | TACR3 (0.43) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21828679 | 0.76 | ALDH1A1 (0.46) | NOTUMSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL21193740 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AL3MBTL1CYP2C19 | |
| SCHEMBL2704313 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176827-A1 | New Pyridine Analogues VII 543 | ASTRAZENECA AB (SE) | 2008-07-24 | — | — | US | disclosed |
| WO-2008085118-A1 | PYRIDINE COMPOUNDS AND THEIR USE AS P2Y12 ANTAGONISTS. | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176827-A1 | New Pyridine Analogues VII 543 | P2RY12, P2RY11, P2RY4 | NOTUM 4541/4885SMN1; SMN2 3504/4885NPC1 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.