Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15352654 | 1.00 | TACR3 (0.43) | TACR3DDB1CRBNHSD11B1L3MBTL1 | |
| SCHEMBL9051840 | 0.85 | NPC1 (0.41) | KMT2AMEN1TACR1PKM | |
| SCHEMBL11538529 | 0.84 | L3MBTL1 (0.49) | L3MBTL1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL4480437 | 0.82 | JAK2 (0.49) | KDM4EGAAPKM | |
| SCHEMBL4784040 | 0.78 | NOTUM (0.45) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1618266 | 0.77 | TACR1 (0.61) | TACR1ALDH1A1 | |
| SCHEMBL6041583 | 0.77 | TACR1 (0.61) | TACR1ALDH1A1 | |
| SCHEMBL2449718 | 0.77 | KMT2A (0.43) | TACR3HSD11B1L3MBTL1KMT2AMEN1 | |
| SCHEMBL2704313 | 0.75 | SMN1; SMN2 (0.41) | L3MBTL1KMT2AMEN1TACR1ALDH1A1 | |
| SCHEMBL27461844 | 0.73 | PLA2G10 (0.35) | TACR3DDB1CRBNHSD11B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | claimed |
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | disclosed |