Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 9/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.32 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.32 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.32 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.32 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.32 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.32 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.32 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.32 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.32 |
| ▸ | PSMB3 | P49720 | 4/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.32 |
| ▸ | PSMA6 | P60900 | 4/20 | 0.32 |
| ▸ | PSMA8 | Q8TAA3 | 4/20 | 0.32 |
| ▸ | PSMB7 | Q99436 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210813 | 1.00 | PSMB5 (0.36) | PSMB5CAPN1PSMB1PSMB11PSMA7 | |
| SCHEMBL3214474 | 0.86 | PSMB11 (0.32) | PSMB5PSMB1PSMB11PSMA7PSMA1 | |
| SCHEMBL4784938 | 0.86 | PSMB11 (0.32) | PSMB5PSMB1PSMB11PSMA7PSMA1 | |
| SCHEMBL3215301 | 0.84 | PDF (0.32) | — | |
| SCHEMBL4737245 | 0.84 | PDF (0.32) | — | |
| Hydrochloric Acid SCHEMBL3202312 | 0.83 | ANPEP (0.42) | PSMB5CAPN1PSMB1PSMB11PSMA7 | |
| Hydrochloric Acid SCHEMBL3202337 | 0.83 | ANPEP (0.42) | PSMB5CAPN1PSMB1PSMB11PSMA7 | |
| SCHEMBL4786196 | 0.81 | PDF (0.46) | — | |
| SCHEMBL3205858 | 0.81 | PDF (0.46) | — | |
| SCHEMBL3219837 | 0.76 | SMN1; SMN2 (0.33) | PSMB5RENPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074035-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2008-06-19 | — | — | WO | disclosed |