Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.32 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.32 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.32 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.32 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.32 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.32 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.32 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.32 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.32 |
| ▸ | PSMB3 | P49720 | 3/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.32 |
| ▸ | PSMA6 | P60900 | 3/20 | 0.32 |
| ▸ | PSMA8 | Q8TAA3 | 3/20 | 0.32 |
| ▸ | PSMB7 | Q99436 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784938 | 1.00 | PSMB11 (0.32) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL4784042 | 0.86 | PSMB5 (0.36) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL3210813 | 0.86 | PSMB5 (0.36) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| Hydrochloric Acid SCHEMBL3224302 | 0.83 | METAP2 (0.32) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| Hydrochloric Acid SCHEMBL3224289 | 0.83 | METAP2 (0.32) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL4737245 | 0.81 | PDF (0.32) | — | |
| SCHEMBL3215301 | 0.81 | PDF (0.32) | — | |
| SCHEMBL4786196 | 0.81 | PDF (0.46) | — | |
| SCHEMBL3205858 | 0.81 | PDF (0.46) | — | |
| SCHEMBL4781054 | 0.77 | GPR88 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303547-A1 | HCV Protease Inhibitors and Uses Thereof | ABBVIE INC (US) | 2013-11-14 | — | — | US | disclosed |
| US-8497275-B2 | HCV protease inhibitors and uses thereof | ABBVIE INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-20100029686-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303547-A1 | HCV Protease Inhibitors and Uses Thereof | SERPINB1, PEPD, PREP | PSMB11 277/4885PSMA7 240/4885PSMB1 189/4885 |
| US-20100029686-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | SERPINB1, PEPD, PREP | PSMB11 277/4885PSMA7 240/4885PSMB1 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.