Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18360451 | 0.73 | CA1 (0.38) | HPGDMAPTL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL12354893 | 0.68 | ADORA3 (0.39) | L3MBTL1KDM4ELMNAHSD17B10 | |
| SCHEMBL2063137 | 0.66 | DAO (0.61) | HPGDMAPTL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5867823 | 0.66 | HPGD (0.45) | HPGDMAPTL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5868086 | 0.65 | CCNA2 (0.66) | — | |
| SCHEMBL14401184 | 0.62 | — | — | |
| SCHEMBL542159 | 0.62 | DAO (0.65) | HPGDMAPTL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL1917679 | 0.62 | MAPT (0.66) | HPGDMAPTL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL11844863 | 0.62 | DAO (0.71) | HPGDMAPTL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL844402 | 0.62 | DAO (0.59) | HPGDMAPTL3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103357-A1 | FUNGICIDAL TRICYCLIC 1,2,4-TRIAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-28 | — | — | WO | disclosed |