Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783215 | 0.80 | PIM1 (0.78) | HSD17B10PIM1KDM4EALDH1A1APAF1 | |
| SCHEMBL32665192 | 0.79 | HSD17B10 (0.49) | HSD17B10PIM1KDM4EALDH1A1APAF1 | |
| SCHEMBL32665398 | 0.74 | ALDH1A1 (0.48) | HSD17B10PIM1KDM4EALDH1A1APAF1 | |
| SCHEMBL32665097 | 0.74 | TP53 (0.49) | HSD17B10PIM1KDM4EALDH1A1APAF1 | |
| SCHEMBL15034199 | 0.74 | PDE10A (0.56) | HTTPOLBPTGER4 | |
| SCHEMBL11751799 | 0.73 | PIM1 (0.79) | HSD17B10PIM1KDM4EALDH1A1APAF1 | |
| SCHEMBL32665000 | 0.72 | ALDH1A1 (0.50) | HSD17B10PIM1KDM4EALDH1A1APAF1 | |
| SCHEMBL32665534 | 0.72 | HSD17B10 (0.46) | HSD17B10PIM1KDM4EALDH1A1APAF1 | |
| SCHEMBL32664943 | 0.72 | ALDH1A1 (0.53) | HSD17B10PIM1KDM4EALDH1A1APAF1 | |
| SCHEMBL32665367 | 0.72 | ALDH1A1 (0.52) | HSD17B10PIM1KDM4EALDH1A1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069500-A1 | TRIAZOLOPYRIDAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-12 | — | — | WO | claimed |
| WO-2008069500-A1 | TRIAZOLOPYRIDAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-12 | — | — | WO | disclosed |