Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.56 |
| ▸ | PPARA | Q07869 | 6/20 | 0.56 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | HCK | P08631 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728555 | 0.85 | PPARA (0.41) | PPARDPPARGPPARACDK8MAPK14 | |
| SCHEMBL4784365 | 0.81 | CDK8 (0.38) | PPARDPPARGPPARACDK8MAPK14 | |
| SCHEMBL4729096 | 0.73 | PPARD (0.73) | PPARDPPARGPPARANR1H4 | |
| SCHEMBL4726352 | 0.72 | PPARG (1.00) | PPARDPPARGPPARAMAPT | |
| SCHEMBL4728588 | 0.71 | PPARD (0.73) | PPARDPPARGPPARA | |
| SCHEMBL4727946 | 0.71 | PPARD (0.73) | PPARDPPARGPPARA | |
| SCHEMBL4726944 | 0.70 | PPARG (0.63) | PPARDPPARGPPARANR1H4 | |
| SCHEMBL15554762 | 0.70 | HTT (0.42) | MAPK14MAPK12MAPK13MAPK11MAPK9 | |
| SCHEMBL15554763 | 0.70 | HTT (0.42) | MAPK14MAPK12MAPK13MAPK11MAPK9 | |
| SCHEMBL16468475 | 0.70 | FKBP1A (0.48) | MAPK14MAPK12MAPK13MAPK11MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |