Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.41 |
| ▸ | PPARG | P37231 | 11/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784362 | 0.85 | PPARD (0.56) | PPARAPPARGPPARDCDK8MAPK14 | |
| SCHEMBL4728557 | 0.82 | CDK8 (0.36) | PPARAPPARDCDK8MAPK14MAPK12 | |
| SCHEMBL4729317 | 0.75 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL4726239 | 0.75 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL4731237 | 0.73 | PPARG (0.73) | PPARAPPARGPPARD | |
| SCHEMBL4728590 | 0.73 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL4726804 | 0.72 | PPARG (0.46) | PPARAPPARGPPARD | |
| SCHEMBL4726805 | 0.72 | PPARG (0.46) | PPARAPPARGPPARD | |
| SCHEMBL4845938 | 0.70 | SAE1 (0.44) | PPARAPPARGPPARD | |
| SCHEMBL4728606 | 0.70 | SAE1 (0.44) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |