Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A7 | Q9GZV3 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233751 | 0.88 | SLC5A7 (0.44) | SLC5A7OPRK1MEN1KMT2AHRH3 | |
| SCHEMBL4784378 | 0.87 | SLC5A7 (0.45) | SLC5A7NPC1RAB9APDE4A | |
| SCHEMBL13699306 | 0.84 | SLC5A7 (0.44) | SLC5A7OPRK1PKMHRH3 | |
| SCHEMBL4683707 | 0.80 | HRH3 (0.41) | SLC5A7HRH3 | |
| SCHEMBL4687069 | 0.80 | HRH3 (0.48) | SLC5A7MEN1KMT2AHRH3 | |
| SCHEMBL4688677 | 0.80 | HRH3 (0.48) | SLC5A7RAB9AHRH3 | |
| SCHEMBL4683166 | 0.80 | HRH3 (0.48) | SLC5A7MEN1KMT2AHRH3 | |
| SCHEMBL4688687 | 0.79 | CCR3 (0.48) | MEN1KMT2AHRH3 | |
| SCHEMBL4236439 | 0.78 | SLC5A7 (0.45) | SLC5A7OPRK1MEN1KMT2AHRH3 | |
| SCHEMBL4683530 | 0.78 | OPRK1 (0.37) | NPC1RAB9AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |