SCHEMBL4784556

SCHEMBL4784556

C=C[CH]c1cnno1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27531080 0.70
SCHEMBL1114746 0.70
SCHEMBL854430 0.59
SCHEMBL685618 0.55
SCHEMBL3642541 0.55
SCHEMBL3691786 0.55
SCHEMBL2662531 0.55
SCHEMBL467889 0.54
Hydrochloric Acid SCHEMBL27598618 0.53
SCHEMBL28176784 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008074450-A2 NON-PEPTIDIC RENIN INHIBITORS NITRODERIVATIVES NICOX S.A. (FR) 2008-06-26 WO claimed
EP-1725530-A1 ORGANIC COMPOUNDS Speedel Experimenta AG (CH) 2006-11-29 EP claimed
WO-2005090304-A1 ORGANIC COMPOUNDS SPEEDEL EXPERIMENTA AG (CH) 2005-09-29 WO claimed
WO-2008074450-A2 NON-PEPTIDIC RENIN INHIBITORS NITRODERIVATIVES NICOX S.A. (FR) 2008-06-26 WO disclosed