Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195416 | 0.71 | KCNA5 (0.46) | ALDH1A1ALOX15MAPTCYP1A2CYP3A4 | |
| SCHEMBL4784582 | 0.67 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTCYP1A2LMNA | |
| SCHEMBL25669745 | 0.65 | CYP1A2 (0.41) | DRD1ALDH1A1L3MBTL1MAPTCYP1A2 | |
| SCHEMBL8404487 | 0.65 | CYP1A2 (0.41) | ALDH1A1MAPTCYP1A2LMNACYP2C19 | |
| SCHEMBL24302564 | 0.64 | MAOA (0.39) | MAPTCYP1A2LMNAGFERCYP2C9 | |
| SCHEMBL10200850 | 0.64 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTCYP1A2LMNA | |
| SCHEMBL13701003 | 0.63 | AURKB (0.46) | ALDH1A1L3MBTL1MAPTCYP1A2MEN1 | |
| SCHEMBL21807407 | 0.63 | PDCD1 (0.37) | LMNAMEN1KMT2A | |
| SCHEMBL21807299 | 0.63 | KDR (0.38) | ALDH1A1L3MBTL1MAPTCYP1A2LMNA | |
| SCHEMBL21783714 | 0.63 | KDR (0.45) | ALDH1A1MAPTCYP3A4LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057402-A2 | N-ARYL-ISOXAZOLOPYRIMIDIN-4-AMINES AND RELATED COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2008-05-15 | — | — | WO | disclosed |