Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495021 | 0.93 | MAPT (0.33) | MAPTOPRM1OPRD1 | |
| SCHEMBL4489808 | 0.89 | MMP2 (0.31) | — | |
| SCHEMBL13712260 | 0.89 | MMP2 (0.31) | — | |
| SCHEMBL4493945 | 0.83 | MMP2 (0.31) | MAPT | |
| SCHEMBL13712266 | 0.83 | MMP2 (0.31) | MAPT | |
| SCHEMBL13712257 | 0.81 | MMP2 (0.31) | — | |
| SCHEMBL13712263 | 0.81 | MMP2 (0.31) | MAPT | |
| SCHEMBL4495276 | 0.81 | MMP2 (0.31) | — | |
| SCHEMBL4480672 | 0.81 | MMP2 (0.31) | — | |
| SCHEMBL4493109 | 0.80 | MMP2 (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073982-A2 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2008-06-19 | — | — | WO | disclosed |