Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784806 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9189981 | 0.77 | HSD17B10 (0.46) | ALDH1A1HPGDL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL11112437 | 0.71 | ALOX5AP (0.46) | HPGDL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25389487 | 0.69 | KMT2A (0.40) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20746423 | 0.69 | ALDH1A1 (0.44) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22858446 | 0.68 | GRIN2D (0.47) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29577389 | 0.68 | GRIN2D (0.47) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31214575 | 0.68 | PROKR1 (0.36) | SCN10AKMT2A | |
| SCHEMBL14500914 | 0.68 | ALDH1A1 (0.56) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4825042 | 0.67 | GAA (0.56) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085119-A1 | NEW PYRIDINE ANALOGUES VIII 518 | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |