Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16338926 | 0.81 | SCN10A (0.35) | KMT2AALDH1A1KIF18ASCN10AMAPK1 | |
| SCHEMBL31214575 | 0.78 | PROKR1 (0.36) | KMT2ASCN10A | |
| SCHEMBL31344078 | 0.77 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1HSD17B10HPGD | |
| SCHEMBL31344082 | 0.77 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1HSD17B10HPGD | |
| SCHEMBL31343943 | 0.75 | SCN10A (0.45) | ALDH1A1CYP2C9KIF18ASCN10ACYP3A4 | |
| SCHEMBL31590723 | 0.74 | USP2 (0.43) | KMT2AMEN1ALDH1A1HSD17B10HPGD | |
| SCHEMBL12983252 | 0.72 | PRKAB2 (0.41) | KMT2A | |
| SCHEMBL12983927 | 0.70 | ADORA2A (0.46) | KIF18A | |
| SCHEMBL12984767 | 0.70 | ADORA2A (0.46) | KIF18A | |
| SCHEMBL12983593 | 0.70 | CHRM4 (0.39) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150201-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |