Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15796737 | 0.84 | ALDH1A1 (0.52) | ALDH1A1PKMERCC5FEN1ALOX15 | |
| SCHEMBL25218986 | 0.83 | ALDH1A1 (0.62) | CYP11B1CYP11B2ALDH1A1PKMERCC5 | |
| SCHEMBL6501472 | 0.81 | ALDH1A1 (0.59) | ALDH1A1PKMERCC5FEN1ALOX15 | |
| SCHEMBL24033865 | 0.81 | ALDH1A1 (0.59) | ALDH1A1PKMERCC5FEN1ALOX15 | |
| SCHEMBL3735937 | 0.80 | ALDH1A1 (0.64) | ALDH1A1PKMERCC5FEN1ALOX15 | |
| SCHEMBL15796733 | 0.80 | ALDH1A1 (0.58) | CYP11B1CYP11B2ALDH1A1PKMERCC5 | |
| SCHEMBL7148471 | 0.78 | ALDH1A1 (0.62) | ALDH1A1PKMERCC5FEN1ALOX15 | |
| SCHEMBL1783911 | 0.77 | ALDH1A1 (0.61) | ALDH1A1PKMERCC5FEN1ALOX15 | |
| SCHEMBL15796827 | 0.77 | ALDH1A1 (0.55) | ALDH1A1PKMERCC5FEN1ALOX15 | |
| SCHEMBL4117033 | 0.75 | CYP11B1 (0.54) | CYP11B1CYP11B2ALOX15TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099019-A1 | 6-HYDROXY-DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |