Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDE8B | O95263 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501472 | 0.89 | ALDH1A1 (0.59) | ALDH1A1PKMALOX15TSHRGAA | |
| SCHEMBL3735937 | 0.83 | ALDH1A1 (0.64) | ALDH1A1PKMALOX15TSHRGAA | |
| SCHEMBL7148471 | 0.81 | ALDH1A1 (0.62) | ALDH1A1PKMALOX15TSHRGAA | |
| SCHEMBL25218986 | 0.81 | ALDH1A1 (0.62) | ALDH1A1PKMALOX15TSHRGAA | |
| SCHEMBL4784872 | 0.81 | CYP11B1 (0.54) | ALDH1A1PKMALOX15TSHRGAA | |
| SCHEMBL1783911 | 0.80 | ALDH1A1 (0.61) | ALDH1A1PKMALOX15TSHRGAA | |
| SCHEMBL15796737 | 0.80 | ALDH1A1 (0.52) | ALDH1A1PKMALOX15TSHRGAA | |
| SCHEMBL6582001 | 0.78 | ERCC5 (0.65) | ALDH1A1PKMALOX15TSHRGAA | |
| SCHEMBL11063190 | 0.78 | ERCC5 (0.62) | ALDH1A1PKMALOX15TSHRGAA | |
| SCHEMBL15796733 | 0.77 | ALDH1A1 (0.58) | ALDH1A1PKMALOX15TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295135-A1 | CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF | ALGEN BIOTECHNOLOGIES, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20230295135-A1 | CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF | ALGEN BIOTECHNOLOGIES, INC. | 2023-09-21 | — | — | US | disclosed |
| CN-116261561-A | Certain chemical compositions and methods of use thereof | 奧基生物技术有限公司 | 2023-06-13 | — | — | CN | disclosed |
| US-11591322-B2 | Certain chemical compositions and methods of use thereof | ALGEN BIOTECHNOLOGIES, INC. (US) | 2023-02-28 | — | — | US | disclosed |
| WO-2021231892-A1 | CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF | ALGEN BIOTECHNOLOGIES, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591322-B2 | Certain chemical compositions and methods of use thereof | CDK9, CDK19, CDK6 | ALDH1A1 1530/4885PKM 581/4885ALOX15 3901/4885 |
| US-20230295135-A1 | CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF | CDK9, CDK19, CDK6 | ALDH1A1 1530/4885PKM 581/4885ALOX15 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.