Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119433 | 0.76 | TSHR (0.31) | TSHR | |
| SCHEMBL17790435 | 0.75 | — | — | |
| SCHEMBL5856356 | 0.72 | TSHR (0.35) | TSHR | |
| SCHEMBL9500035 | 0.72 | TRIM24 (0.32) | — | |
| SCHEMBL9336430 | 0.71 | ALDH1A1 (0.47) | TSHR | |
| SCHEMBL123127 | 0.71 | ALDH1A1 (0.47) | TSHR | |
| Iodide SCHEMBL2127044 | 0.69 | ALDH1A1 (0.45) | TSHR | |
| SCHEMBL309527 | 0.69 | ALDH1A1 (0.45) | TSHR | |
| Water SCHEMBL4753900 | 0.69 | ALDH1A1 (0.45) | TSHR | |
| Bromide SCHEMBL7687601 | 0.69 | ALDH1A1 (0.45) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099019-A1 | 6-HYDROXY-DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008099019-A1 | 6-HYDROXY-DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |