Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL16332561 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Bromide SCHEMBL6739425 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Bromide SCHEMBL6744490 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Bromide SCHEMBL16333039 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| SCHEMBL9336430 | 0.97 | ALDH1A1 (0.47) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| SCHEMBL123127 | 0.97 | ALDH1A1 (0.47) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Water SCHEMBL4753900 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| SCHEMBL309527 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Iodide SCHEMBL2127044 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| SCHEMBL9413781 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633597-B2 | Use of zeolite NU-86 for naphtha catalytic cracking | IFP Energies Nouvelles (FR) | 2020-04-28 | — | — | US | disclosed |
| EP-2794102-B1 | METHOD FOR PREPARING A CATALYST USABLE IN HYDROCONVERSION AND INCLUDING AT LEAST ONE NU-86 ZEOLITE | IFP ENERGIES NOW (FR) | 2020-03-25 | — | — | EP | disclosed |
| US-20190161685-A1 | USE OF ZEOLITE NU-86 FOR NAPHTHA CATALYTIC CRACKING | IFP Energies Nouvelles (FR) | 2019-05-30 | — | — | US | disclosed |
| CN-109312237-A | Application of NU-86 zeolite in catalytic cracking method of naphtha | IFP 新能源公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-103998130-B | Including at least one NU-86 zeolites, the catalyst of at least one USY zeolite and porous inorganic substrate and the method for carrying out hydro-conversion hydrocarbon raw material using the catalyst | IFP 新能源公司 | 2018-11-13 | — | — | CN | disclosed |
| US-9925533-B2 | Method of preparing a catalyst usable in hydroconversion comprising at least one zeolite NU-86 | IFP Energies Nouvelles (FR) | 2018-03-27 | — | — | US | disclosed |
| US-9890050-B2 | Molecular sieve material, its synthesis and use | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2018-02-13 | — | — | US | disclosed |
| EP-2817262-B1 | MOLECULAR SIEVE MATERIAL, ITS SYNTHESIS AND USE | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2017-11-15 | — | — | EP | disclosed |
| US-9718050-B2 | Catalyst comprising at least one zeolite NU-86, at least one zeolite USY and a porous mineral matrix and process for hydroconversion of hydrocarbon feeds using said catalyst | IFP Energies Nouvelles (FR) | 2017-08-01 | — | — | US | disclosed |
| CN-104010729-B | The method that preparation comprises the catalyst that can be used for hydro-conversion of at least one NU 86 zeolite | IFP 新能源公司 | 2017-03-01 | — | — | CN | disclosed |
| US-20150025291-A1 | Molecular Sieve Material, Its Synthesis and Use | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| EP-2817262-A1 | MOLECULAR SIEVE MATERIAL, ITS SYNTHESIS AND USE | ExxonMobil Chemical Patents Inc. (US) | 2014-12-31 | — | — | EP | disclosed |
| CN-104159849-A | MOLECULAR SIEVE MATERIAL, ITS SYNTHESIS AND USE | EXXONMOBIL CHEM PATENTS INC | 2014-11-19 | — | — | CN | disclosed |
| US-20140326641-A1 | METHOD OF PREPARING A CATALYST USABLE IN HYDROCONVERSION COMPRISING AT LEAST ONE ZEOLITE NU-86 | IFP Energies Nouvelles (FR) | 2014-11-06 | — | — | US | disclosed |
| CN-104010729-A | Method for preparing a catalyst usable in hydroconversion and including at least one nu-86 zeolite | IFP Energies Nouvelles | 2014-08-27 | — | — | CN | disclosed |
| CN-103998130-A | Catalyst including at least one NU-86 zeolite, at least one USY zeolite, and a porous inorganic matrix, and method for the hydroconversion of hydrocarbon feedstocks using said catalyst | IFP Energies Nouvelles | 2014-08-20 | — | — | CN | disclosed |
| WO-2013126140-A1 | MOLECULAR SIEVE MATERIAL, ITS SYNTHESIS AND USE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-08-29 | — | — | WO | disclosed |
| US-6337428-B1 | OLIGOMERIZING C2-C8 OLEFINS; MATRIX AND NU-86 ZEOLITE, PARTIALLY ACID FORM, COMPRISING SILICON AND AT LEAST ONE ELEMENT FROM OF ALUMINUM, IRON, GALLIUM AND BORON THAT IS EXTRACTED FROM FRAMEWORK | INSTITUT FRANCAIS DU PETROLE (FR) | 2002-01-08 | — | — | US | disclosed |
| US-6165439-A | Dealuminated NU-86 zeolite and its use for the conversion of hydrocarbons | INSTITUT FRANCAIS DU PETROLE (FR) | 2000-12-26 | — | — | US | disclosed |
| US-6077420-A | Process for cracking hydrocarbon feeds using a catalyst comprising a dealuminated NU-86 zeolite | INSTITUT FRANCAIS DU PETROLE (FR) | 2000-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025291-A1 | Molecular Sieve Material, Its Synthesis and Use | RPS17, MMP17, MRPS27 | ALDH1A1 4657/4885ALOX15 2723/4885MAOA 4374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.