Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785666 | 0.88 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL4787101 | 0.85 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| SCHEMBL3067509 | 0.84 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL2056870 | 0.83 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL4786006 | 0.82 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL28304845 | 0.79 | NPC1 (0.54) | — | |
| SCHEMBL4743875 | 0.79 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL1398853 | 0.78 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL28874732 | 0.78 | NPC1 (0.55) | — | |
| SCHEMBL2056940 | 0.78 | HCRTR1 (0.40) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087611-A2 | PYRROLIDINE- AND PIPERIDINE- BIS-AMIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-07-24 | — | — | WO | claimed |