Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632745 | 0.87 | HDAC3 (0.45) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL4633717 | 0.85 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL4632690 | 0.85 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL4633411 | 0.85 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL14069718 | 0.83 | HDAC3 (0.45) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL4735050 | 0.82 | MMP9 (0.42) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL4633718 | 0.81 | HDAC3 (0.47) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL14159252 | 0.81 | HDAC3 (0.47) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL4632734 | 0.81 | ACACB (0.42) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL4633744 | 0.81 | MMP2 (0.45) | HDAC3HDAC1HDAC2HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071453-A1 | 1,2-DIARYLACETYLENE DERIVATIVES OF ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-06-19 | — | — | WO | disclosed |