Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786160 | 0.94 | CNR1 (0.38) | CNR1BACE1FAAH | |
| SCHEMBL4732724 | 0.82 | CNR1 (0.47) | CNR1FAAH | |
| SCHEMBL4734518 | 0.82 | CNR1 (0.35) | CNR1BACE1 | |
| SCHEMBL4520943 | 0.81 | CNR1 (0.44) | CNR1FAAH | |
| SCHEMBL4740565 | 0.81 | BACE1 (0.36) | CNR1BACE1 | |
| SCHEMBL4738661 | 0.80 | PKM (0.38) | CNR1BACE1 | |
| SCHEMBL4740558 | 0.80 | CNR1 (0.35) | CNR1BACE1NOTUM | |
| SCHEMBL4737236 | 0.78 | CNR1 (0.39) | CNR1BACE1FAAH | |
| SCHEMBL4738306 | 0.77 | CNR1 (0.41) | CNR1BACE1FAAH | |
| SCHEMBL4737591 | 0.77 | BACE1 (0.39) | CNR1BACE1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076044-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |