Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE6A | P16499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467061 | 0.87 | MEN1 (0.62) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL1688423 | 0.87 | PDE5A (0.46) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL1285850 | 0.87 | KMT2A (0.49) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL18530485 | 0.87 | KDM4E (0.44) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL27294587 | 0.85 | MEN1 (0.54) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL1178299 | 0.83 | CA2 (0.56) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL10518080 | 0.83 | MEN1 (0.52) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL1645669 | 0.82 | KIF11 (0.38) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL23575405 | 0.81 | MEN1 (0.52) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL29532116 | 0.81 | KDM4E (0.47) | MEN1KMT2ATHRBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090434-A1 | SUBSTITUTED N-BICYCLICALKYL BICYCLIC CARBOXYAMIDE COMPOUNDS | PFIZER JAPAN INC. (JP) | 2008-07-31 | — | — | WO | disclosed |
| WO-2007133637-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |