Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692325 | 0.90 | CPA1 (0.43) | CTSSCTSKSLC7A5ITGA4ITGB7 | |
| SCHEMBL7692324 | 0.90 | CPA1 (0.43) | CTSSCTSKSLC7A5ITGA4ITGB7 | |
| SCHEMBL27166271 | 0.81 | CTSS (0.43) | CTSSCTSKSLC7A5ITGA4ITGB7 | |
| SCHEMBL10604721 | 0.81 | CTSS (0.43) | CTSSCTSKSLC7A5ITGA4ITGB7 | |
| SCHEMBL6661008 | 0.81 | CTSS (0.44) | CTSSCTSKSLC7A5ESR1ESR2 | |
| SCHEMBL8766144 | 0.81 | CTSS (0.44) | CTSSCTSKSLC7A5ESR1ESR2 | |
| SCHEMBL4778626 | 0.81 | CTSS (0.44) | CTSSCTSKSLC7A5ESR1ESR2 | |
| SCHEMBL7782926 | 0.80 | PPARG (0.41) | CTSSCTSKITGA4ITGB7PPARG | |
| SCHEMBL23567069 | 0.80 | CTSS (0.44) | CTSSCTSKSLC7A5ITGA4ITGB7 | |
| SCHEMBL22804104 | 0.80 | SLC7A5 (0.45) | CTSSCTSKSLC7A5ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131047-A2 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF TO MODULATE LIPID METABOLISM | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-10-30 | — | — | WO | disclosed |