Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128945 | 0.82 | PPARG (0.45) | PPARGPPARAITGA4ITGB7NR1D1 | |
| SCHEMBL9803399 | 0.81 | ALDH1A1 (0.39) | PPARGPPARAITGA4ITGB7NR1D1 | |
| SCHEMBL28743946 | 0.80 | PPARG (0.44) | PPARGPPARAITGA4ITGB7NR1D1 | |
| SCHEMBL4785949 | 0.80 | CTSS (0.41) | PPARGPPARAITGA4ITGB7CTSS | |
| SCHEMBL15577663 | 0.79 | CTSS (0.44) | PPARGPPARAITGA4ITGB7MEN1 | |
| SCHEMBL4516266 | 0.79 | NPC1 (0.39) | PPARGPPARAITGA4ITGB7NR1D1 | |
| SCHEMBL8371983 | 0.78 | ALDH1A1 (0.41) | PPARGPPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL8373359 | 0.78 | ALDH1A1 (0.41) | PPARGPPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL11648038 | 0.78 | ALDH1A1 (0.41) | PPARGPPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL18301525 | 0.78 | SLC7A5 (0.43) | ITGA4ITGB7CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713093-B1 | Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER AG (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5663044-A | Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0713093-A2 | Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | Bayer Corporation (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0158204-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, CONTAINING A ZWITTERION COUPLING AGENT | MILES INC. (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0157326-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, ESTERASE AND PROTEASE IN A TEST SAMPLE | MILES INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4657855-A | DIP-AND-READ, UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4637979-A | Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent | MILES LABORATORIES, INC. (US) | 1987-01-20 | — | — | US | disclosed |