Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912400 | 0.87 | HSD17B10 (0.77) | HSD17B10L3MBTL1ALDH1A1KDM4EKLKB1 | |
| SCHEMBL3765456 | 0.86 | KLKB1 (0.53) | HSD17B10L3MBTL1ALDH1A1KDM4EKLKB1 | |
| SCHEMBL27370953 | 0.85 | HSD17B10 (0.56) | HSD17B10L3MBTL1ALDH1A1KDM4EKLKB1 | |
| SCHEMBL369349 | 0.84 | L3MBTL1 (0.58) | HSD17B10L3MBTL1KLKB1RAB9APOLB | |
| SCHEMBL17221323 | 0.84 | KLKB1 (0.56) | HSD17B10L3MBTL1ALDH1A1KDM4EKLKB1 | |
| SCHEMBL30730236 | 0.84 | HSD17B10 (0.48) | HSD17B10L3MBTL1ALDH1A1MAPK10KDM4E | |
| SCHEMBL30730185 | 0.84 | POLB (0.62) | L3MBTL1ALDH1A1MAPK10KDM4EPOLB | |
| SCHEMBL4785257 | 0.84 | KLKB1 (0.55) | L3MBTL1ALDH1A1KDM4EKLKB1KLK1 | |
| SCHEMBL17895755 | 0.83 | L3MBTL1 (0.60) | HSD17B10L3MBTL1ALDH1A1KDM4EKLKB1 | |
| Hydrochloric Acid SCHEMBL31549317 | 0.83 | L3MBTL1 (0.57) | HSD17B10L3MBTL1KLKB1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089436-A2 | CRYSTALLINE FORMS OF HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008089436-A2 | CRYSTALLINE FORMS OF HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2008-07-24 | — | — | WO | disclosed |