Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.63 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236455 | 0.88 | PKM (0.63) | PKMTAS1R3TAS1R1POLBMAPK1 | |
| SCHEMBL4240208 | 0.86 | PKM (0.63) | PKMTAS1R3TAS1R1POLBMAPK1 | |
| SCHEMBL4240960 | 0.84 | PKM (0.58) | PKMTAS1R3TAS1R1POLBMAPK1 | |
| SCHEMBL4744588 | 0.84 | PKM (0.57) | PKMTAS1R3TAS1R1POLBMAPK1 | |
| SCHEMBL4240206 | 0.84 | PKM (0.60) | PKMTAS1R3TAS1R1POLBMAPK1 | |
| SCHEMBL4785970 | 0.80 | EPHX2 (0.56) | POLBRAB9A | |
| SCHEMBL4233787 | 0.78 | PKM (0.56) | PKMTAS1R3TAS1R1POLBMAPK1 | |
| SCHEMBL4233255 | 0.76 | PKM (0.59) | PKMTAS1R3TAS1R1MAPK1NPC1 | |
| SCHEMBL4228345 | 0.75 | MAPT (0.53) | PKMTAS1R3TAS1R1POLBMAPK1 | |
| SCHEMBL4226776 | 0.74 | PKM (0.54) | PKMTAS1R3TAS1R1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |