Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688990 | 0.87 | PKM (0.50) | PKMTAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL4683259 | 0.86 | PKM (0.49) | PKMTAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL4236455 | 0.84 | PKM (0.63) | PKMTAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL4785963 | 0.84 | PKM (0.63) | PKMTAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL4233255 | 0.84 | PKM (0.59) | PKMCYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL4744778 | 0.82 | PKM (0.52) | PKMCYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL4240208 | 0.81 | PKM (0.63) | PKMTAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL4689054 | 0.81 | TAS1R3 (0.72) | PKMCYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL4240960 | 0.80 | PKM (0.58) | PKMTAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL4240206 | 0.80 | PKM (0.60) | PKMTAS1R3TAS1R1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |