Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787185 | 0.87 | KMO (0.50) | KMT2AMEN1HSD17B10KDM4EALOX15 | |
| SCHEMBL14103925 | 0.84 | KMO (0.47) | KMT2AMEN1HSD17B10KDM4EALOX15 | |
| SCHEMBL7893969 | 0.78 | KMT2A (0.85) | KMT2AMEN1HSD17B10KDM4EALOX15 | |
| SCHEMBL4738640 | 0.75 | KMT2A (0.76) | KMT2AMEN1HSD17B10KDM4EALOX15 | |
| SCHEMBL17146882 | 0.73 | MEN1 (0.60) | KMT2AMEN1HSD17B10KDM4EALOX15 | |
| SCHEMBL30674460 | 0.73 | KMT2A (0.83) | KMT2AMEN1HSD17B10KDM4EALOX15 | |
| SCHEMBL4786608 | 0.73 | KMO (0.38) | KMT2AMEN1KDM4EPDE4BALDH1A1 | |
| SCHEMBL15001940 | 0.72 | KMT2A (0.62) | KMT2AMEN1HSD17B10KDM4EALOX15 | |
| SCHEMBL21255799 | 0.72 | MEN1 (1.00) | KMT2AMEN1HSD17B10KDM4EALOX15 | |
| SCHEMBL2873071 | 0.72 | MAPK1 (0.65) | KMT2AMEN1HSD17B10KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095852-A1 | BRONCHORELAXING ARYLAMIDES | RESPIRATORIUS AB (SE) | 2008-08-14 | — | — | WO | disclosed |