Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785886 | 0.86 | HPGD (0.57) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL7893969 | 0.84 | KMT2A (0.85) | KMT2AMEN1MAPK1HSD17B10KDM4E | |
| SCHEMBL4785434 | 0.82 | MEN1 (0.68) | KMT2AMEN1MAPK1HSD17B10KDM4E | |
| SCHEMBL30674460 | 0.80 | KMT2A (0.83) | KMT2AMEN1MAPK1HSD17B10KDM4E | |
| SCHEMBL21255799 | 0.80 | MEN1 (1.00) | KMT2AMEN1MAPK1HSD17B10KDM4E | |
| SCHEMBL14103923 | 0.80 | HPGD (0.55) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL14925200 | 0.76 | KMT2A (0.62) | KMT2AMEN1MAPK1HSD17B10KDM4E | |
| SCHEMBL5125288 | 0.76 | KMT2A (0.68) | KMT2AMEN1MAPK1HSD17B10KDM4E | |
| SCHEMBL4786100 | 0.75 | KMT2A (0.64) | KMT2AMEN1MAPK1HSD17B10KDM4E | |
| SCHEMBL5127400 | 0.75 | KMT2A (0.67) | KMT2AMEN1MAPK1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095852-A1 | BRONCHORELAXING ARYLAMIDES | RESPIRATORIUS AB (SE) | 2008-08-14 | — | — | WO | disclosed |