SCHEMBL4786141

SCHEMBL4786141

Cc1cc(Oc2c(C3CCC3)nn(C3CS(=O)(=O)C3)c2CO)cc(C)c1C#N

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4854390 0.96
SCHEMBL14021466 0.88
SCHEMBL4731703 0.83
SCHEMBL4919594 0.82
SCHEMBL4784279 0.82 KDM1A (0.31)
SCHEMBL4782054 0.81 L3MBTL1 (0.33)
SCHEMBL4752257 0.79 PDE10A (0.34)
SCHEMBL4904300 0.79 PGR (0.34) DPP4KCNH2
SCHEMBL4782032 0.77 L3MBTL1 (0.36)
SCHEMBL4748729 0.76 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008135824-A1 OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY PFIZER LIMITED (GB) 2008-11-13 WO disclosed