Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAP2 | P11137 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788030 | 0.83 | SLC9A1 (0.40) | SLC9A1PARP1CHEK2MAPK1 | |
| SCHEMBL4787686 | 0.82 | SLC9A1 (0.51) | SLC9A1PIN1CHEK2 | |
| SCHEMBL4785742 | 0.81 | SLC9A1 (0.53) | SLC9A1PIN1 | |
| SCHEMBL4785802 | 0.78 | SLC9A1 (0.40) | SLC9A1PIN1CHEK2ALDH1A1 | |
| SCHEMBL4787499 | 0.77 | SLC9A1 (0.56) | SLC9A1ALDH1A1RXFP1 | |
| SCHEMBL4787790 | 0.76 | SLC9A1 (0.54) | SLC9A1PIN1 | |
| SCHEMBL4786233 | 0.76 | SLC9A1 (0.68) | SLC9A1 | |
| SCHEMBL4788116 | 0.76 | SLC9A1 (0.40) | SLC9A1CHEK2ALDH1A1 | |
| SCHEMBL4787952 | 0.75 | SLC9A1 (0.56) | SLC9A1PIN1 | |
| SCHEMBL4787537 | 0.74 | SLC9A1 (0.54) | SLC9A1PARP1ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008111794-A1 | 4-METHYLIMIDAZOL-5-YLCARBONYLGUANIDINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE ISCHEMIC HEART DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-09-18 | — | — | WO | disclosed |