SCHEMBL4786233

SCHEMBL4786233

Cc1nc(-c2cc(Cl)cc(Cl)c2)[nH]c1C(=O)N=C(N)N

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 19/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4786228 0.76 SLC9A1 (0.46) SLC9A1
SCHEMBL11860062 0.67 SLC9A1 (0.56) SLC9A1
SCHEMBL8342056 0.65 MAPK1 (0.50)
SCHEMBL6313758 0.65 SLC9A1 (0.54) SLC9A1
Hydrochloric Acid SCHEMBL8504416 0.64 SLC9A1 (0.50) SLC9A1
SCHEMBL4744491 0.62 GDA (0.43) SLC9A1
SCHEMBL4786226 0.62 SLC9A1 (0.52) SLC9A1
SCHEMBL8345138 0.60 SIRT2 (0.59)
SCHEMBL4943405 0.60 SLC9A1 (1.00) SLC9A1
SCHEMBL8534449 0.60 SLC9A1 (0.72) SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008111794-A1 4-METHYLIMIDAZOL-5-YLCARBONYLGUANIDINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE ISCHEMIC HEART DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-09-18 WO disclosed