Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.44 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784998 | 0.92 | PTGES (0.45) | PTGESHDAC2HDAC1PRSS12HDAC3 | |
| SCHEMBL4847730 | 0.91 | PTGES (0.45) | PTGESHDAC2HDAC1PRSS12 | |
| SCHEMBL4786533 | 0.86 | PTGES (0.45) | PTGESHDAC1PRSS12 | |
| SCHEMBL4786443 | 0.84 | PTGES (0.44) | PTGESHDAC1PRSS12 | |
| SCHEMBL4786434 | 0.82 | PTGES (0.44) | PTGESPRSS12 | |
| SCHEMBL4786267 | 0.80 | PTGES (0.58) | PTGES | |
| SCHEMBL4786016 | 0.79 | PTGES (0.44) | PTGESHDAC2HDAC1PRSS12HDAC3 | |
| SCHEMBL3796343 | 0.79 | PTGES (0.42) | PTGESHDAC2HDAC1HDAC3 | |
| SCHEMBL4785770 | 0.79 | PTGES (0.42) | PTGESPRSS12 | |
| SCHEMBL4785278 | 0.78 | PTGES (0.52) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |